How to build an AI-first organization | Ethan Mollick
Most companies are using AI to cut costs. Ethan Mollick argues that the biggest mistake companies make is thinking too small.
In the first episode of Strange Loop, Wharton professor and leading AI researcher Ethan Mollick joins Sana founder and CEO Joel Hellermark for a candid and wide-ranging conversation about the rapidly changing world of AI at work.
They explore how AI is not just an efficiency tool but a turning point—one that forces a choice between incremental optimization and transformational scale. The discussion covers the roots of machine intelligence, the relevance of AGI, and what it takes to build organizations designed from the ground up for an AI-native future.
What’s in this episode:
- Why most companies are underestimating what AI makes possible
- The tension between using AI for efficiency vs. scaling ambition
- How traditional org charts, built for a human-only workforce, are breaking
- The collapse of apprenticeship and its long-term implications
- How prompting is becoming a foundational business skill
- Why “cheating” with AI may be the new form of learning
- The risks of using AI to optimize the past instead of inventing the future
- What it means to build truly AI-native teams and organizations
Strange Loop is a podcast about how artificial intelligence is reshaping the systems we live and work in. Each episode features deep, unscripted conversations with thinkers and builders reimagining intelligence, leadership, and the architectures of progress. The goal is not just to follow AI’s trajectory, but to question the assumptions guiding it.
Subscribe for more conversations at the edge of AI and human knowledge.
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00:20 - Origins: AI in the early days at MIT
01:53 - Defining and testing intelligence: Beyond the Turing test
06:35 - Redesigning organizations for the AI era
08:56 - Human augmentation or replacement
14:58 - Navigating AI's jagged frontier
17:18 - The 3 ingredients for successful AI adoption
23:31 - Roles to hire for an AI-first world
33:41 - Do orgs need a Chief AI officer?
39:45 - The interface for AI and human collaboration
43:50 - Rethinking the goals of enterprise AI
49:15 - The case for abundance
52:30 - Best and worse case scenarios
58:51 - Avoiding the trap of enterprise AI KPIs
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